Docétaxel

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Docétaxel

API

N° CAS 114977-28-5

Antineoplastic drugs

  • Docetaxel is an alkaloid obtained by hemisynthesis from a molecule extracted from the leaves of the European yew tree.
  • It acts by promoting the assembly of tubulin into stable microtubules and inhibiting their depolymerization leading to a marked decrease in free tubulin. The binding of docetaxel to microtubules does not alter the number of protofilaments.

Formule : C43H53NO14

Masse moléculaire : 807,88 g/mol

Pharmacopée : EP/USP

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