Magnésium d'ésoméprazole trihydraté

API

N° CAS 217087-09-7

Drugs for acid related disorders

• Esomeprazole Magnesium trihydrate is the magnesium trihydrate salt of esomeprazole, the S-isomer of omeprazole, with gastric proton pump inhibitor activity.
• White or Almost white crystalline powder.
• It is protonated and converted to the active achiral sulfenamide. It then forms one or more covalent disulfide bonds with the hydrogen-potassium-adenosine triphosphatase of the proton pump, thereby inhibiting its activity and the secretion by the parietal cells of H+ ions into the gastric lumen.