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Colchicine
API
N° CAS 64-86-8
Anti-inflammatory and antirheumatic products
- Colchicine is a very toxic tricyclic alkaloid, extracted from colchicum, mainly fall colchicum.
- White or pale yellow crystalline powder
- It disorganizes the cytoskeleton by binding to tubulin, which inhibits the polymerization of the main components of microtubules. This blocks mitosis but also inhibits the mobility and activity of neutrophils, resulting in an anti-inflammatory effect.
Formule : C22H25NO6
Masse moléculaire : 399,44 g/mol
Pharmacopée : EP/USP
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