N° CAS 302962-49-8
- Dasatinib is a multi-inhibitor of type I tyrosine kinase.
- Pale yellow solid
- It competes for ATP in the active site of the kinase but does not displace the GFR loop. The 2-chloro-6-methylphenyl group is located in the hydrophobic pocket, the aminothiazole nitrogens establish hydrogen bonds with the amino acids of the protein's halo region.
Origine : Chemical
Formule : C22H26ClN7O2S
Masse moléculaire : 488,01 g/mol
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