Doxifluridine

API

N° CAS 05/09/3094

Antineoplastic drugs

• Doxifluridine is a second generation nucleoside analogue prodrug used as a cytostatic agent in chemotherapy.
• White or Almost white crystalline powder.
• It is converted to 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.