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Fénofibrate
API
N° CAS 49562-28-9
Cardiac therapy
- Fenofibrate is a synthetic derivative of phenoxyisobutyric acid and a prodrug with antihyperlipidemic activity.
- White or Almost white crystalline powder.
- Through activation of PPAR alpha, it increases lipolysis and removal of atherogenic triglyceride-rich particles from plasma by activation of lipoprotein lipase and reduction of apoprotein CIII production. Activation of PPAR alpha also leads to an increase in the synthesis of apoproteins AI and AII.
Origine : Chemical
Formule : C20H21ClO4
Masse moléculaire : 360,83 g/mol
Pharmacopée : EP/USP/JP
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