Floxuridine

API

N° CAS 50-91-9

Antineoplastic drugs

• Floxuridine is a pyrimidine analogue used as an antineoplastic agent.
• White or Almost white crystalline powder.
• It inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity. This agent is also metabolized to fluorouracil and other metabolites that can be incorporated into RNA and inhibit the utilization of preformed uracil in RNA synthesis.