Gémifloxacine

API

N° CAS 175463-14-6

Antibiotics

• Gemifloxacin is a broad-spectrum quinolone antibacterial agent.
• It enters bacterial cells by diffusion through integral membrane porin pathway before targeting both DNA gyrase and topoisomerase IV, two enzymes critical for DNA replication and repair. This agent binds to the DNA/DNA-gyrase complex and inhibits the A subunits of the enzyme thereby preventing the bacterial chromosome from rejoining.