Ibandronate de sodium

API

N° CAS 138844-81-2

Drugs for treatment of bone diseases

• Ibandronate sodium is the sodium salt form of ibandronic acid, a synthetic nitrogen-containing bisphosphonate.
• White to off-white crystalline powder.
• It inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastasis and corticosteroid-related bone pain.