Lévothyroxine sodique

API

N° CAS 55-03-8

Thyroid therapy

• Levothyroxine sodium is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine that is similar to the endogenous hormone produced by the thyroid gland.
• In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine. It enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins necessary for the regulation of cellular respiration, thermogenesis, cell growth and differentiation, and protein, carbohydrate and lipid metabolism.