Lovastatine

API

N° CAS 75330-75-5

Drugs used in diabetes

• Lovastatin is a statin, a family of lipid-lowering drugs.
• White or very pale yellow crystal powder.
• It's an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. Mevalonate is a required building block for cholesterol biosynthesis and lovastatin interferes with its production by acting as a reversible competitive inhibitor for HMG-CoA, which binds to the HMG-CoA reductase.