Nystatine

API

N° CAS 1400-61-9

Antimycotics for systemic use

• Nystatin is an antimycotic polyene whose structure is very close to Amphotericin B.
• Yellow powder.
• It binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage, acidification, and death of the fungus.