Phosphate d'estramustine sodique

API

N° CAS 52205-73-9

Chemotherapy

• Estramustine phosphate sodium is the disodium salt, monohydrate of estramustine phosphate, a synthetic molecule that combines estradiol and yperite through a carbamate linkage.
• Estramustine and its major metabolite bind to microtubule- and tubulin-associated proteins, thereby inhibiting microtubule dynamics and causing anaphase arrest in a dose-dependent manner.