Prednisolone

API

N° CAS 50-24-8

Corticosteroids for systemic use

• Prednisolone is a synthetic glucocorticoid, used as an anti-inflammatory in many forms.
• Odorless crystalline solid
• As a glucocorticoid, the lipophilic structure of prednisolone allows it to readily cross the cell membrane where it then binds to its respective glucocorticoid receptor located in the cytoplasm. Upon binding, the formation of the GC/RGC complex results in dissociation of the glucocorticoid receptor chaperone proteins, allowing the complex to move into the nucleus. The complex binds to specific DNA binding sites.