N° CAS 85622-93-1
- Temozolomide is a triazene derivative that is used as an anti-cancer agent.
- Yellow or slightly pale yellow crystalline powder.
- Temozolomide undergoes spontaneous hydrolysis at physiological pH to 3-methyl-(triazen-1-yl)imidazole-4-carboxamide which alkylates guanine in the O and N position, the cytotoxic lesions that are subsequently developed are thought to result in aberrant DNA repair.
Origine : Chemical
Formule : C6H6N6O2
Masse moléculaire : 194,15 g/mol
Pharmacopée : EP/USP
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